Nicotine replacement therapy in pregnancy

Nicotine replacement therapy in pregnancy.

Cigarette smoking is a major modifiable cause of adverse pregnancy outcomes. Nicotine-replacement therapy (NRT) is recommended in guidelines, but its efficacy and safety during pregnancy is uncertain. This multicentre double-blind trial recruited 1050 pregnant participants who were in their 12–24 weeks’ gestation periods. All of them smoked ≥5 cigarettes per day (median 20). Participants were r...

[Nicotine replacement therapy during pregnancy].

In spite of the fact that smoking is the main cause of obstetric morbidity and mortality, 20% of North American women smoke during pregnancy. In Spain, this figure is as high as 30% to 35%. Treating smoking addiction in these patients should be the first and most important therapeutic measure undertaken by health professionals responsible for the care of pregnant women. All experts recommend th...

A randomized trial of nicotine-replacement therapy patches in pregnancy.

BACKGROUND Nicotine-replacement therapy is effective for smoking cessation outside pregnancy and its use is widely recommended during pregnancy. We investigated the efficacy and safety of nicotine patches during pregnancy. METHODS We recruited participants from seven hospitals in England who were 16 to 50 years of age with pregnancies of 12 to 24 weeks' gestation and who smoked five or more c...

Nicotine replacement therapy in pregnancy: use or avoid?

Nicotine replacement and behavioral therapy for smoking cessation in pregnancy.

BACKGROUND This study examines whether adding nicotine replacement therapy (NRT) to cognitive-behavioral therapy (CBT) for pregnant smokers increases rates of smoking cessation. METHODS An open-label randomized trial (Baby Steps, n=181) of CBT-only versus CBT+NRT (choice of patch, gum, or lozenge; 1:2 randomization) was used. Data were collected from 2003 through 2005; analyses were conducted...